BDBM50300027 (S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylamino)-7-(2-methoxyethoxy)quinazolin-6-yl]pyrrolidine-2-carboxamide::CHEMBL569880

SMILES COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3F)c2cc1NC(=O)[C@@H]1CCCN1C(=O)C=C

InChI Key InChIKey=JTLHPKSZESHKCP-IBGZPJMESA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300027   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed